Acid reflux medication uk apcalis SX Oral Jelly is a variation of Generic Cialis. The main component of Apcalis is Tadalafil. Apcalis is an effective, reversible, selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Cialis leads to increase of cGMP levels in the cavernous body of penis. It results in the relaxation of arterial smooth muscles and blood flow to the tissues of the penis that causes erections. Cialis has no effect when sexual stimulation is absent. Apcalis improves erection and let’s achieve a successful sexual intercourse. The drug acts for 36 hours. If sexual arousal is present the effect appears even after 16 minutes after the medication was taken. Many people using this medicine do not have serious side effects. Before taking Dapoxetine to tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have bipolar confusion, eye, liver or kidney problems. Aged people can be more sensitive to the side effects of the medicine. During the pregnancy, this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.