Can you drink on trimethoprim 200mg a high fat meal may delay the time of the effect of this drug. The recommended dose of Cialis is 20 mg it should be taken at least 16 minutes before the sexual activity. The effect persists for 36 hours. Take Cialis once daily and do not exceed the recommended dose. Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.