Orlistat 60 mg dosage a high fat meal may delay the time of the effect of this drug. You can assign tramadol in the form of rectal (for introduction into the rectum) candles containing 0.1 g (100 mg), 1 candle up to 4 times per day. When administered intravenously, it has an analgesic effect in 5-10 minutes, when administered orally – in 30-40 minutes. Valid for 3-5 hours You can not appoint tramadol in acute alcohol intoxication (poisoning); patients with hypersensitivity to narcotic analgesics; patients taking MAO inhibitors. A pregnant appointment should be made with extreme caution. Children under the age of 14 do not prescribe the drug.