Postponing periods medicine dapoxetine belongs to a class of selective serotonin reuptake inhibitors (SSRIs). This short-acting inhibitor is used to treat premature ejaculation in men. You can assign tramadol in the form of rectal (for introduction into the rectum) candles containing 0.1 g (100 mg), 1 candle up to 4 times per day. When administered intravenously, it has an analgesic effect in 5-10 minutes, when administered orally – in 30-40 minutes. Valid for 3-5 hours Most usual side effects of Apcalis are facial flushing (reddening), headaches, stomach upset, diarrhea, flu-like symptoms and nausea. In more rare cases low blood pressure, blurred vision and changes in color vision, and abnormal ejaculation may occur. Prolonged erections or priapism (painful erections lasting more than 6 hours) are also possible. If your erection is longer than 4 hours, seek for immediate medical help as it may permanently damage your penis. Aggravation of heart problems in patients with pre-existing heart disease using Apcalis was reported.