Price of esomeprazole apcalis SX Oral Jelly is a variation of Generic Cialis. The main component of Apcalis is Tadalafil. Apcalis is an effective, reversible, selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Cialis leads to increase of cGMP levels in the cavernous body of penis. It results in the relaxation of arterial smooth muscles and blood flow to the tissues of the penis that causes erections. Cialis has no effect when sexual stimulation is absent. Apcalis improves erection and let’s achieve a successful sexual intercourse. The drug acts for 36 hours. If sexual arousal is present the effect appears even after 16 minutes after the medication was taken. Consult with your doctor before using. Use no more than was prescribed. Take it orally, generally three times daily during (or up to one hour after) each main meal that contains fat. You should take a multivitamin addition including vitamins A, D, E, and K to ensure good supply. The addition should be taken at least two hours before or after you take this medication, such as before going to bed. The recommended dose for adults and children under 12 years is one 120-milligram capsule 3 times daily. Note: this instruction presented here just for review. It’s very necessary to consult with your doctor before using. It helps you to get the best results. Kamagra Oral Jelly is contraindicated in patients taking another medicine to treat impotence or using a nitrate drug for chest pain or heart problems. This medicine should not be taken by women and children as well as in patients with a known hypersensitivity to any component of the tablet.