Primolut n to prepone periods apcalis SX Oral Jelly is a variation of Generic Cialis. The main component of Apcalis is Tadalafil. Apcalis is an effective, reversible, selective inhibitor of phosphodiesterase type 5 (PDE 5) specific to cyclic guanosine monophosphate (cGMP). When sexual stimulation causes local release of nitric oxide, inhibition of PDE 5 by Cialis leads to increase of cGMP levels in the cavernous body of penis. It results in the relaxation of arterial smooth muscles and blood flow to the tissues of the penis that causes erections. Cialis has no effect when sexual stimulation is absent. Apcalis improves erection and let’s achieve a successful sexual intercourse. The drug acts for 36 hours. If sexual arousal is present the effect appears even after 16 minutes after the medication was taken. Inform your doctor if you have hypotension or hypertension, cardiac failure, coronary artery disease, deformations of the penis, sickle-cell anaemia, multiple myeloma, leukaemia, retinitis pigmentosa, and also a history of cardiac dysfunction, myocardial infarction, stroke arrhythmia, life-threatening arrhythmia, cardiovascular problems, allergies. Do not take Super P-Force together with other ED medication.