Xenical otc version try not to eat grapefruit or drink grapefruit juice while you are being treated with Sildenafil. It is preferable not to use Apcalis with grapefruit juice, alcoholic beverages, tobacco. If you smoke tobacco and take Apcalis concomitantly this may lead to a condition called NAION (sudden optic nerve-related vision loss). Inform your doctor before to take Apcalis if you have abnormal penis, including curved penis and birth defects of the penis, had coronary artery disease, arrhythmia, angina, heart attack or heart failure, hypo- or hypertension, bleeding, stomach ulcers, diabetes, hyperlipidemia (excess of lipids in the blood), sickle-cell anemia, liver or kidney failure in history. Viagra is contraindicated in patients taking another medicine to treat impotence or using a nitrate drug for chest pain or heart problems. This medicine should not be taken by women and children as well as in patients with a known hypersensitivity to any component of the tablet.